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Bile Acid–Drug Interaction via Organic Anion-Transporting Polypeptide 4C1 Is a Potential Mechanism of Altered Pharmacokinetics of Renally Excreted Drugs

Patients with liver diseases not only experience the adverse effects of liver-metabolized drugs, but also the unexpected adverse effects of renally excreted drugs. Bile acids alter the expression of renal drug transporters, however, the direct effects of bile acids on drug transport remain unknown....

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Detalles Bibliográficos
Autores principales:	Yamauchi, Minami, Sato, Toshihiro, Otake, Ayana, Kumondai, Masaki, Sato, Yu, Kikuchi, Masafumi, Maekawa, Masamitsu, Yamaguchi, Hiroaki, Abe, Takaaki, Mano, Nariyasu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369231/ https://www.ncbi.nlm.nih.gov/pubmed/35955643 http://dx.doi.org/10.3390/ijms23158508

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