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mTOR Complex 1 Content and Regulation Is Adapted to Animal Longevity

Decreased content and activity of the mechanistic target of rapamycin (mTOR) signalling pathway, as well as the mTOR complex 1 (mTORC1) itself, are key traits for animal species and human longevity. Since mTORC1 acts as a master regulator of intracellular metabolism, it is responsible, at least in p...

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Detalles Bibliográficos
Autores principales: Mota-Martorell, Natalia, Jové, Mariona, Pamplona, Reinald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369240/
https://www.ncbi.nlm.nih.gov/pubmed/35955882
http://dx.doi.org/10.3390/ijms23158747

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