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Toll-like Receptor 7 (TLR7) Is Expressed in Adipocytes and the Pharmacological TLR7 Agonist Imiquimod and Adipocyte-Derived Cell-Free Nucleic Acids (cfDNA) Regulate Adipocyte Function

Endosome-localized Toll-like receptors (TLRs) 3 and 9 are expressed and functionally active in adipocytes. The functionality and role of TLR7 in adipocyte biology and innate immunity of adipose tissue (AT) is poorly characterized. We analyzed TLR7 mRNA and protein expression in murine 3T3-L1 and pri...

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Detalles Bibliográficos
Autores principales:	Thomalla, Miriam, Schmid, Andreas, Hehner, Julia, Koehler, Sebastian, Neumann, Elena, Müller-Ladner, Ulf, Schäffler, Andreas, Karrasch, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369246/ https://www.ncbi.nlm.nih.gov/pubmed/35955609 http://dx.doi.org/10.3390/ijms23158475

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