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Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody

Regulatory T cells (T(regs)) are major drivers behind immunosuppressive mechanisms and present a major hurdle for cancer therapy. T(regs) are characterized by a high expression of CD25, which is a potentially valuable target for T(reg) depletion to alleviate immune suppression. The preclinical anti-...

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Detalles Bibliográficos
Autores principales:	van Elsas, Marit J., van der Schoot, Johan M. S., Bartels, Alexander, Steuten, Kas, van Dalen, Duco, Wijfjes, Zacharias, Figdor, Carl G., van Hall, Thorbald, van der Burg, Sjoerd H., Verdoes, Martijn, Scheeren, Ferenc A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369266/ https://www.ncbi.nlm.nih.gov/pubmed/35955841 http://dx.doi.org/10.3390/ijms23158707

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