Cargando…

Inhibition of Monoacylglycerol Lipase by NSD1819 as an Effective Strategy for the Endocannabinoid System Modulation against Neuroinflammation-Related Disorders

Neuroinflammation is a key pathological event shared by different diseases affecting the nervous system. Since the underlying mechanism of neuroinflammation is a complex and multifaceted process, current pharmacological treatments are unsatisfactory—a reason why new therapeutic approaches are mandat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Micheli, Laura, Maramai, Samuele, Toti, Alessandra, Ferrara, Valentina, Ciampi, Clara, Di Cesare Mannelli, Lorenzo, Ghelardini, Carla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369272/ https://www.ncbi.nlm.nih.gov/pubmed/35955562 http://dx.doi.org/10.3390/ijms23158428

Ejemplares similares

Endocannabinoid control of neuroinflammation in traumatic brain injury by monoacylglycerol lipase in astrocytes
por: Chen, Chu
Publicado: (2022)

Effects of Ultramicronized N-Palmitoylethanolamine Supplementation on Tramadol and Oxycodone Analgesia and Tolerance Prevention
por: Micheli, Laura, et al.
Publicado: (2022)

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
por: Schlosburg, Joel E., et al.
Publicado: (2010)

Anti-Hyperalgesic Efficacy of Acetyl L-Carnitine (ALCAR) Against Visceral Pain Induced by Colitis: Involvement of Glia in the Enteric and Central Nervous System
por: Lucarini, Elena, et al.
Publicado: (2023)

Neuronal and Astrocytic Monoacylglycerol Lipase Limit the Spread of Endocannabinoid Signaling in the Cerebellum123
por: Chen, Yao, et al.
Publicado: (2016)

Efficacy of a vegetal mixture composed of Zingiber officinale, Echinacea purpurea, and Centella asiatica in a mouse model of neuroinflammation: In vivo and ex vivo analysis
por: Micheli, Laura, et al.
Publicado: (2022)

Interferon-gamma and neuropathy: balance between pain and neuroprotection
por: Ferrara, Valentina, et al.
Publicado: (2022)

Ultramicronized N-Palmitoylethanolamine Regulates Mast Cell-Astrocyte Crosstalk: A New Potential Mechanism Underlying the Inhibition of Morphine Tolerance
por: Toti, Alessandra, et al.
Publicado: (2023)

Coordinated regulation of endocannabinoid-mediated retrograde synaptic suppression in the cerebellum by neuronal and astrocytic monoacylglycerol lipase
por: Liu, Xiaojie, et al.
Publicado: (2016)

Protective and Pain-Killer Effects of AMC3, a Novel N-Formyl Peptide Receptors (FPRs) Modulator, in Experimental Models of Rheumatoid Arthritis
por: Ferrara, Valentina, et al.
Publicado: (2023)

Monoacylglycerol Lipase Regulates Fever Response
por: Sanchez-Alavez, Manuel, et al.
Publicado: (2015)

Endocannabinoid Modulation Using Monoacylglycerol Lipase Inhibition in Tourette Syndrome: A Phase 1 Randomized, Placebo-Controlled Study
por: Müller-Vahl, Kirsten R., et al.
Publicado: (2021)

Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism
por: Margiotta, Francesco, et al.
Publicado: (2022)

Over-Expression of Monoacylglycerol Lipase (MGL) in Small Intestine Alters Endocannabinoid Levels and Whole Body Energy Balance, Resulting in Obesity
por: Chon, Su-Hyoun, et al.
Publicado: (2012)

Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol
por: Kishimoto, Yasushi, et al.
Publicado: (2015)

Beneficial Effects of Eruca sativa Defatted Seed Meal on Visceral Pain and Intestinal Damage Resulting from Colitis in Rats
por: Lucarini, Elena, et al.
Publicado: (2022)

Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
por: Rengachari, Srinivasan, et al.
Publicado: (2013)

Conformational gating, dynamics and allostery in human monoacylglycerol lipase
por: Tyukhtenko, Sergiy, et al.
Publicado: (2020)

Effect of monoacylglycerol lipase on the tumor growth in endometrial cancer
por: Li, Xin, et al.
Publicado: (2019)

The Efficacy of Camelina sativa Defatted Seed Meal against Colitis-Induced Persistent Visceral Hypersensitivity: The Relevance of PPAR α Receptor Activation in Pain Relief
por: Lucarini, Elena, et al.
Publicado: (2022)

Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina
por: Cécyre, Bruno, et al.
Publicado: (2014)

N-terminal domain replacement changes an archaeal monoacylglycerol lipase into a triacylglycerol lipase
por: Soni, Surabhi, et al.
Publicado: (2019)

O-13: INHIBITION OF THE ENDOCANNABINOID REGULATING ENZYME MONOACYLGLYCEROL LIPASE AMELIORATES THE HYPER-NOCICEPTIVE PHENOTYPE IN THE BERKELEY MOUSE MODEL OF SICKLE CELL DISEASE
por: K., GOLDSBOROUGH, et al.
Publicado: (2022)

Monoacylglycerol lipase reprograms lipid precursors signaling in liver disease
por: Tardelli, Matteo
Publicado: (2020)

Targeting Monoacylglycerol Lipase in Pursuit of Therapies for Neurological and Neurodegenerative Diseases
por: Zanfirescu, Anca, et al.
Publicado: (2021)

Monoacylglycerol lipase reprograms hepatocytes and macrophages to promote liver regeneration
por: Allaire, Manon, et al.
Publicado: (2023)

Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice
por: Costola-de-Souza, Carolina, et al.
Publicado: (2013)

Effects of Distal Mutations on the Structure, Dynamics and Catalysis of Human Monoacylglycerol Lipase
por: Tyukhtenko, Sergiy, et al.
Publicado: (2018)

Monoacylglycerol Lipase Knockdown Inhibits Cell Proliferation and Metastasis in Lung Adenocarcinoma
por: Zhang, Hao, et al.
Publicado: (2020)

A New Ultrasensitive Bioluminescence-Based Method for Assaying Monoacylglycerol Lipase
por: Miceli, Matteo, et al.
Publicado: (2021)

Discovery of 8-prenylnaringenin from hop (Humulus lupulus L.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer's disease
por: Tung, Min-Che, et al.
Publicado: (2021)

Correction: Discovery of 8-prenylnaringenin from hop (Humulus lupulus L.) as a potent monoacylglycerol lipase inhibitor for treatments of neuroinflammation and Alzheimer’s disease
por: Tung, Min-Che, et al.
Publicado: (2022)

Monoacylglycerol Lipases Act as Evolutionarily Conserved Regulators of Non-oxidative Ethanol Metabolism
por: Heier, Christoph, et al.
Publicado: (2016)

Effect of Monoacylglycerol Lipase Inhibition on Intestinal Permeability of Rats With Severe Acute Pancreatitis
por: Wang, Jing, et al.
Publicado: (2022)

Reversible Monoacylglycerol Lipase Inhibitors: Discovery of a New Class of Benzylpiperidine Derivatives
por: Bononi, Giulia, et al.
Publicado: (2022)

Intranasal Low-Dose Naltrexone Against Opioid Side Effects: A Preclinical Study
por: Micheli, Laura, et al.
Publicado: (2020)

Low dose native type II collagen prevents pain in a rat osteoarthritis model
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2013)

PPAR-γ Impairment Alters Peroxisome Functionality in Primary Astrocyte Cell Cultures
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2014)

Ultramicronized N-Palmitoylethanolamine Supplementation for Long-Lasting, Low-Dosed Morphine Antinociception
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2018)

Broad-spectrum neuroprotection exerted by DDD-028 in a mouse model of chemotherapy-induced neuropathy
por: Lucarini, Elena, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_0fgsle0fcshd7152fr1esam3ss