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Metabolic Remodeling with Hepatosteatosis Induced Vascular Oxidative Stress in Hepatic ERK2 Deficiency Mice with High Fat Diets

We previously demonstrated the marked hepatosteatosis and endothelial dysfunction in hepatocyte-specific ERK2 knockout mice (LE2KO) with a high-fat/high-sucrose diet (HFHSD), but detailed metabolic changes and the characteristics in insulin-sensitive organs were not tested. This study aimed to chara...

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Detalles Bibliográficos
Autores principales:	Kujiraoka, Takehiko, Kagami, Kazuki, Kimura, Toyokazu, Ishinoda, Yuki, Shiraishi, Yasunaga, Ido, Yasuo, Endo, Shogo, Satoh, Yasushi, Adachi, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369278/ https://www.ncbi.nlm.nih.gov/pubmed/35955653 http://dx.doi.org/10.3390/ijms23158521

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