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Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development

Ten-eleven translocation (Tet) dioxygenases can induce DNA demethylation by catalyzing 5-methylcytosine(5mC) to 5-hydroxymethylcytosine(5hmC), and play important roles during mammalian development. In mouse, Tet1 and Tet2 are not expressed in pronucleus-staged embryos and are not involved in the gen...

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Detalles Bibliográficos
Autores principales:	Qi, Qi, Wang, Qianqian, Liu, Kailing, Bian, Jiangyue, Yu, Zhixuan, Hou, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369288/ https://www.ncbi.nlm.nih.gov/pubmed/35955629 http://dx.doi.org/10.3390/ijms23158495

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