Endoglin and MMP14 Contribute to Ewing Sarcoma Spreading by Modulation of Cell–Matrix Interactions

Endoglin (ENG) is a mesenchymal stem cell (MSC) marker typically expressed by active endothelium. This transmembrane glycoprotein is shed by matrix metalloproteinase 14 (MMP14). Our previous work demonstrated potent preclinical activity of first-in-class anti-ENG antibody-drug conjugates as a nascen...

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Detalles Bibliográficos
Autores principales: Puerto-Camacho, Pilar, Díaz-Martín, Juan, Olmedo-Pelayo, Joaquín, Bolado-Carrancio, Alfonso, Salguero-Aranda, Carmen, Jordán-Pérez, Carmen, Esteban-Medina, Marina, Álamo-Álvarez, Inmaculada, Delgado-Bellido, Daniel, Lobo-Selma, Laura, Dopazo, Joaquín, Sastre, Ana, Alonso, Javier, Grünewald, Thomas G. P., Bernabeu, Carmelo, Byron, Adam, Brunton, Valerie G., Amaral, Ana Teresa, Álava, Enrique De
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369355/
https://www.ncbi.nlm.nih.gov/pubmed/35955799
http://dx.doi.org/10.3390/ijms23158657

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