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What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review

Intramedullary spinal cord abscesses (ISCA) are rare. Typical symptoms include signs of infection and neurological deficits. Symptoms among (younger) children can be highly uncharacteristic. Therefore, prompt and proper diagnoses may be difficult. Typical therapeutic options include antibiotics and...

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Autores principales: Szmyd, Bartosz, Jabbar, Redwan, Lusa, Weronika, Karuga, Filip Franciszek, Pawełczyk, Agnieszka, Błaszczyk, Maciej, Jankowski, Jakub, Sołek, Julia, Wysiadecki, Grzegorz, Tubbs, R. Shane, Iwanaga, Joe, Radek, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369492/
https://www.ncbi.nlm.nih.gov/pubmed/35956164
http://dx.doi.org/10.3390/jcm11154549
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author Szmyd, Bartosz
Jabbar, Redwan
Lusa, Weronika
Karuga, Filip Franciszek
Pawełczyk, Agnieszka
Błaszczyk, Maciej
Jankowski, Jakub
Sołek, Julia
Wysiadecki, Grzegorz
Tubbs, R. Shane
Iwanaga, Joe
Radek, Maciej
author_facet Szmyd, Bartosz
Jabbar, Redwan
Lusa, Weronika
Karuga, Filip Franciszek
Pawełczyk, Agnieszka
Błaszczyk, Maciej
Jankowski, Jakub
Sołek, Julia
Wysiadecki, Grzegorz
Tubbs, R. Shane
Iwanaga, Joe
Radek, Maciej
author_sort Szmyd, Bartosz
collection PubMed
description Intramedullary spinal cord abscesses (ISCA) are rare. Typical symptoms include signs of infection and neurological deficits. Symptoms among (younger) children can be highly uncharacteristic. Therefore, prompt and proper diagnoses may be difficult. Typical therapeutic options include antibiotics and neurosurgical exploration and drainage. In this review, we analyze published cases of ISCA among children. Most pediatric cases were found to be under the age of 6 years. The typical symptoms included motor deficits in 89.06%, infection signs in 85.94%, and sensory deficits in 39.06%. Urinary dysfunction was observed in 43.75%, and bowel dysfunction in 17.19%. The predisposing factors included dermal sinuses, (epi)dermoid cysts, prior infection, iatrogenic disorder, and trauma. The most common pathogens were: Staphylococcus aureus, Mycobacterium tuberculosis, Escherichia coli, and Proteus mirabilis. The pediatric population has good outcomes as 45.93% of patients had complete neurological recovery and only 26.56% had residual neurological deficits. Fifteen (23.44%) had persistent neurological deficits. Only one (1.56%) patient died with an ISCA. In two (3.13%) cases, there were no details about follow-up examinations.
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spelling pubmed-93694922022-08-12 What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review Szmyd, Bartosz Jabbar, Redwan Lusa, Weronika Karuga, Filip Franciszek Pawełczyk, Agnieszka Błaszczyk, Maciej Jankowski, Jakub Sołek, Julia Wysiadecki, Grzegorz Tubbs, R. Shane Iwanaga, Joe Radek, Maciej J Clin Med Review Intramedullary spinal cord abscesses (ISCA) are rare. Typical symptoms include signs of infection and neurological deficits. Symptoms among (younger) children can be highly uncharacteristic. Therefore, prompt and proper diagnoses may be difficult. Typical therapeutic options include antibiotics and neurosurgical exploration and drainage. In this review, we analyze published cases of ISCA among children. Most pediatric cases were found to be under the age of 6 years. The typical symptoms included motor deficits in 89.06%, infection signs in 85.94%, and sensory deficits in 39.06%. Urinary dysfunction was observed in 43.75%, and bowel dysfunction in 17.19%. The predisposing factors included dermal sinuses, (epi)dermoid cysts, prior infection, iatrogenic disorder, and trauma. The most common pathogens were: Staphylococcus aureus, Mycobacterium tuberculosis, Escherichia coli, and Proteus mirabilis. The pediatric population has good outcomes as 45.93% of patients had complete neurological recovery and only 26.56% had residual neurological deficits. Fifteen (23.44%) had persistent neurological deficits. Only one (1.56%) patient died with an ISCA. In two (3.13%) cases, there were no details about follow-up examinations. MDPI 2022-08-04 /pmc/articles/PMC9369492/ /pubmed/35956164 http://dx.doi.org/10.3390/jcm11154549 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Szmyd, Bartosz
Jabbar, Redwan
Lusa, Weronika
Karuga, Filip Franciszek
Pawełczyk, Agnieszka
Błaszczyk, Maciej
Jankowski, Jakub
Sołek, Julia
Wysiadecki, Grzegorz
Tubbs, R. Shane
Iwanaga, Joe
Radek, Maciej
What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title_full What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title_fullStr What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title_full_unstemmed What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title_short What Is Currently Known about Intramedullary Spinal Cord Abscess among Children? A Concise Review
title_sort what is currently known about intramedullary spinal cord abscess among children? a concise review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369492/
https://www.ncbi.nlm.nih.gov/pubmed/35956164
http://dx.doi.org/10.3390/jcm11154549
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