Cargando…

Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1

Deciphering the protein posttranslational modification (PTM) code is one of the greatest biochemical challenges of our time. Phosphorylation and ubiquitylation are key PTMs that dictate protein function, recognition, sub-cellular localization, stability, turnover and fate. Hence, failures in their r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mann, Guy, Sulkshane, Prasad, Sadhu, Pradeep, Ziv, Tamar, Glickman, Michael H., Brik, Ashraf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369648/ https://www.ncbi.nlm.nih.gov/pubmed/35956818 http://dx.doi.org/10.3390/molecules27154867

Ejemplares similares

Synthesis and delivery of a stable phosphorylated ubiquitin probe to study ubiquitin conjugation in mitophagy
por: Mann, Guy, et al.
Publicado: (2021)

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
por: Kazlauskaite, Agne, et al.
Publicado: (2015)

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation
por: Faienza, Fiorella, et al.
Publicado: (2023)

Impact of different ionization states of phosphorylated Serine-65 on ubiquitin structure and interactions
por: Kazansky, Yaniv, et al.
Publicado: (2018)

Nek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1
por: Mbom, Bertrade C., et al.
Publicado: (2014)

Hunting for Serine 276-Phosphorylated p65
por: Spooren, Anneleen, et al.
Publicado: (2010)

LATS1/WARTS phosphorylates MYPT1 to counteract PLK1 and regulate mammalian mitotic progression
por: Chiyoda, Tatsuyuki, et al.
Publicado: (2012)

Multiplexed Delivery of Synthetic (Un)Conjugatable Ubiquitin and SUMO2 Enables Simultaneous Monitoring of Their Localization and Function in Live Cells
por: Mann, Guy, et al.
Publicado: (2022)

Spatial Separation of Plk1 Phosphorylation and Activity
por: Bruinsma, Wytse, et al.
Publicado: (2015)

Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death
por: O'Donovan, D S, et al.
Publicado: (2013)

Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis
por: Yamaguchi, Tomoya, et al.
Publicado: (2005)

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser(65)
por: Kazlauskaite, Agne, et al.
Publicado: (2014)

Mitotic Disassembly of Nuclear Pore Complexes Involves CDK1- and PLK1-Mediated Phosphorylation of Key Interconnecting Nucleoporins
por: Linder, Monika I., et al.
Publicado: (2017)

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly
por: Tang, Danming, et al.
Publicado: (2012)

Phosphorylation of Parkin at serine 65 is essential for its activation in vivo
por: McWilliams, Thomas G., et al.
Publicado: (2018)

Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryos
por: Tavernier, Nicolas, et al.
Publicado: (2015)

On-Demand Detachment of Succinimides on Cysteine to Facilitate (Semi)Synthesis of Challenging Proteins
por: Vamisetti, Ganga B., et al.
Publicado: (2020)

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis
por: Wauer, Tobias, et al.
Publicado: (2015)

Dual control by Cdk1 phosphorylation of the budding yeast APC/C ubiquitin ligase activator Cdh1
por: Höckner, Sebastian, et al.
Publicado: (2016)

CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation
por: Seibert, Markus, et al.
Publicado: (2019)

Ubiquitination of Intramitochondrial Proteins: Implications for Metabolic Adaptability
por: Sulkshane, Prasad, et al.
Publicado: (2020)

Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System
por: Inglis, Kelly J., et al.
Publicado: (2009)

PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis
por: Lee, Kwanwoo, et al.
Publicado: (2011)

PLK1 Interacts and Phosphorylates Axin That Is Essential for Proper Centrosome Formation
por: Ruan, Ka, et al.
Publicado: (2012)

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1
por: Ehlén, Åsa, et al.
Publicado: (2020)

PLK1 Regulates MicroRNA Biogenesis through Drosha Phosphorylation
por: Fletcher, Claire Emily, et al.
Publicado: (2023)

Synthetic Proteins behind the Plasma Barrier: Molecular Spies
por: Mann, Guy, et al.
Publicado: (2022)

Examining the role of phosphorylation of p19(INK4d) in its stability and ubiquitination using chemical protein synthesis
por: Msallam, Muna, et al.
Publicado: (2020)

Exploration of CTCF post-translation modifications uncovers Serine-224 phosphorylation by PLK1 at pericentric regions during the G2/M transition
por: Del Rosario, Brian C, et al.
Publicado: (2019)

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6
por: Aquino Perez, Cecilia, et al.
Publicado: (2020)

Protein Kinase A-mediated Serine 35 Phosphorylation Dissociates Histone H1.4 from Mitotic Chromosome
por: Chu, Chi-Shuen, et al.
Publicado: (2011)

Phosphorylation of LSD1 by PLK1 promotes its chromatin release during mitosis
por: Peng, Bin, et al.
Publicado: (2017)

Plk1 regulates spindle orientation by phosphorylating NuMA in human cells
por: Sana, Shrividya, et al.
Publicado: (2018)

Polθ is phosphorylated by PLK1 to repair double-strand breaks in mitosis
por: Gelot, Camille, et al.
Publicado: (2023)

Analysis of mitotic phosphorylation of Borealin
por: Kaur, Harpreet, et al.
Publicado: (2007)

Evolutionary patterns of phosphorylated serines
por: Kurmangaliyev, Yerbol Z, et al.
Publicado: (2011)

Regulation of APC Activity by Phosphorylation and Regulatory Factors
por: Kotani, Shuji, et al.
Publicado: (1999)

Regulation of divalent metal transporter-1 by serine phosphorylation
por: Seo, Young Ah, et al.
Publicado: (2016)

Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
por: Yu, Lan, et al.
Publicado: (2021)

The interrelationship between APC/C and Plk1 activities in centriole disengagement
por: Hatano, Toshiyuki, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_77jmk9cmp9siff83l9k4bjltl8