Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex

This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communi...

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Detalles Bibliográficos
Autores principales: Foryś-Basiejko, Małgorzata, Kotulska, Katarzyna, Maryniak, Agnieszka, Siłuszyk, Agata, Szkop, Monika, Borkowska, Julita, Sugalska, Monika, Głowacka-Walas, Jagoda, Jóźwiak, Sergiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369686/
https://www.ncbi.nlm.nih.gov/pubmed/35956179
http://dx.doi.org/10.3390/jcm11154564
Descripción
Sumario:This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay.

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