Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex

This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communi...

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Autores principales: Foryś-Basiejko, Małgorzata, Kotulska, Katarzyna, Maryniak, Agnieszka, Siłuszyk, Agata, Szkop, Monika, Borkowska, Julita, Sugalska, Monika, Głowacka-Walas, Jagoda, Jóźwiak, Sergiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369686/
https://www.ncbi.nlm.nih.gov/pubmed/35956179
http://dx.doi.org/10.3390/jcm11154564
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author Foryś-Basiejko, Małgorzata
Kotulska, Katarzyna
Maryniak, Agnieszka
Siłuszyk, Agata
Szkop, Monika
Borkowska, Julita
Sugalska, Monika
Głowacka-Walas, Jagoda
Jóźwiak, Sergiusz
author_facet Foryś-Basiejko, Małgorzata
Kotulska, Katarzyna
Maryniak, Agnieszka
Siłuszyk, Agata
Szkop, Monika
Borkowska, Julita
Sugalska, Monika
Głowacka-Walas, Jagoda
Jóźwiak, Sergiusz
author_sort Foryś-Basiejko, Małgorzata
collection PubMed
description This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay.
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spelling pubmed-93696862022-08-12 Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex Foryś-Basiejko, Małgorzata Kotulska, Katarzyna Maryniak, Agnieszka Siłuszyk, Agata Szkop, Monika Borkowska, Julita Sugalska, Monika Głowacka-Walas, Jagoda Jóźwiak, Sergiusz J Clin Med Article This paper aimed to assess language development in infants and toddlers with tuberous sclerosis complex (TSC) and epilepsy, which increase the risk of autism spectrum disorder. We assessed language development in 61 patients with TSC at 8–36 months using a standardized Speech Development and Communication Inventory tool. The results showed differences in outcomes due to the duration of the seizures and the number of drugs (pFDR = 0.007 **—pFDR = 0.037 *). Children with TSC with longer epilepsy duration and receiving more antiepileptic drugs have a greater risk of language development delay. MDPI 2022-08-04 /pmc/articles/PMC9369686/ /pubmed/35956179 http://dx.doi.org/10.3390/jcm11154564 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Foryś-Basiejko, Małgorzata
Kotulska, Katarzyna
Maryniak, Agnieszka
Siłuszyk, Agata
Szkop, Monika
Borkowska, Julita
Sugalska, Monika
Głowacka-Walas, Jagoda
Jóźwiak, Sergiusz
Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title_full Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title_fullStr Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title_full_unstemmed Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title_short Epilepsy and Language Development in 8–36-Month-Old Toddlers with Tuberous Sclerosis Complex
title_sort epilepsy and language development in 8–36-month-old toddlers with tuberous sclerosis complex
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369686/
https://www.ncbi.nlm.nih.gov/pubmed/35956179
http://dx.doi.org/10.3390/jcm11154564
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