Using Interpretable Machine Learning to Identify Baseline Predictive Factors of Remission and Drug Durability in Crohn’s Disease Patients on Ustekinumab

Ustekinumab has shown efficacy in Crohn’s Disease (CD) patients. To identify patient profiles of those who benefit the most from this treatment would help to position this drug in the therapeutic paradigm of CD and generate hypotheses for future trials. The objective of this analysis was to determin...

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Detalles Bibliográficos
Autores principales: Chaparro, María, Baston-Rey, Iria, Fernández Salgado, Estela, González García, Javier, Ramos, Laura, Diz-Lois Palomares, María Teresa, Argüelles-Arias, Federico, Iglesias Flores, Eva, Cabello, Mercedes, Rubio Iturria, Saioa, Núñez Ortiz, Andrea, Charro, Mara, Ginard, Daniel, Dueñas Sadornil, Carmen, Merino Ochoa, Olga, Busquets, David, Iyo, Eduardo, Gutiérrez Casbas, Ana, Ramírez de la Piscina, Patricia, Boscá-Watts, Marta Maia, Arroyo, Maite, García, María José, Hinojosa, Esther, Gordillo, Jordi, Martínez Montiel, Pilar, Velayos Jiménez, Benito, Quílez Ivorra, Cristina, Vázquez Morón, Juan María, Huguet, José María, González-Lama, Yago, Muñagorri Santos, Ana Isabel, Amo, Víctor Manuel, Martín Arranz, María Dolores, Bermejo, Fernando, Martínez Cadilla, Jesús, Rubín de Célix, Cristina, Fradejas Salazar, Paola, López San Román, Antonio, Jiménez, Nuria, García-López, Santiago, Figuerola, Anna, Jiménez, Itxaso, Martínez Cerezo, Francisco José, Taxonera, Carlos, Varela, Pilar, de Francisco, Ruth, Monfort, David, Molina Arriero, Gema, Hernández-Camba, Alejandro, García Alonso, Francisco Javier, Van Domselaar, Manuel, Pajares-Villarroya, Ramón, Núñez, Alejandro, Rodríguez Moranta, Francisco, Marín-Jiménez, Ignacio, Robles Alonso, Virginia, Martín Rodríguez, María del Mar, Camo-Monterde, Patricia, García Tercero, Iván, Navarro-Llavat, Mercedes, García, Lara Arias, Hervías Cruz, Daniel, Kloss, Sebastian, Passey, Alun, Novella, Cynthia, Vispo, Eugenia, Barreiro-de Acosta, Manuel, Gisbert, Javier P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369748/
https://www.ncbi.nlm.nih.gov/pubmed/35956133
http://dx.doi.org/10.3390/jcm11154518

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