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Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects

Local random skin flaps and skin grafts are everyday surgical techniques used to reconstruct skin defects. Although their clinical advantages and disadvantages are well known, there are still uncertainties with respect to their long-term results. Hence, the aim of this study was to evaluate outcomes...

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Autores principales: Martinovic, Dinko, Lupi-Ferandin, Slaven, Tokic, Daria, Usljebrka, Mislav, Rados, Andrija, Pojatina, Ante, Kadic, Sanja, Puizina, Ema, Mihovilovic, Ante, Kumric, Marko, Vilovic, Marino, Leskur, Dario, Bozic, Josko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369767/
https://www.ncbi.nlm.nih.gov/pubmed/35956089
http://dx.doi.org/10.3390/jcm11154471
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author Martinovic, Dinko
Lupi-Ferandin, Slaven
Tokic, Daria
Usljebrka, Mislav
Rados, Andrija
Pojatina, Ante
Kadic, Sanja
Puizina, Ema
Mihovilovic, Ante
Kumric, Marko
Vilovic, Marino
Leskur, Dario
Bozic, Josko
author_facet Martinovic, Dinko
Lupi-Ferandin, Slaven
Tokic, Daria
Usljebrka, Mislav
Rados, Andrija
Pojatina, Ante
Kadic, Sanja
Puizina, Ema
Mihovilovic, Ante
Kumric, Marko
Vilovic, Marino
Leskur, Dario
Bozic, Josko
author_sort Martinovic, Dinko
collection PubMed
description Local random skin flaps and skin grafts are everyday surgical techniques used to reconstruct skin defects. Although their clinical advantages and disadvantages are well known, there are still uncertainties with respect to their long-term results. Hence, the aim of this study was to evaluate outcomes more than one-year post operatively using objective measurement devices. The study included 31 facial defects reconstructed with local random flap, 30 facial defects reconstructed with split-thickness skin grafts (STSGs) and 30 facial defects reconstructed with full-thickness skin grafts (FTSGs). Skin quality was objectively evaluated using MP6 noninvasive probes (Courage + Khazaka GmbH, Cologne, Germany), which measure melanin count, erythema, hydration, sebum, friction and transepidermal water loss. The results showed that there were no significant differences in melanin count, erythema, hydration, sebum level, friction value and transepidermal water loss (TEWL) between the site reconstructed with random local flaps and the same site on the healthy contralateral side of the face. However, both FTSGs and STSGs showed significantly higher levels in terms of TEWL and erythema, whereas the levels of hydration, sebum and friction were significantly lower compared to the healthy contralateral side. Moreover, STSGs resulted in a significant difference in melanin count. These findings imply that the complex pathophysiology of the wound-healing process possibly results in better skin-quality outcomes for random local flaps than skin autografts. Consequently, this suggests that random local flaps should be implemented whenever possible for the reconstruction of facial region defects.
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spelling pubmed-93697672022-08-12 Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects Martinovic, Dinko Lupi-Ferandin, Slaven Tokic, Daria Usljebrka, Mislav Rados, Andrija Pojatina, Ante Kadic, Sanja Puizina, Ema Mihovilovic, Ante Kumric, Marko Vilovic, Marino Leskur, Dario Bozic, Josko J Clin Med Article Local random skin flaps and skin grafts are everyday surgical techniques used to reconstruct skin defects. Although their clinical advantages and disadvantages are well known, there are still uncertainties with respect to their long-term results. Hence, the aim of this study was to evaluate outcomes more than one-year post operatively using objective measurement devices. The study included 31 facial defects reconstructed with local random flap, 30 facial defects reconstructed with split-thickness skin grafts (STSGs) and 30 facial defects reconstructed with full-thickness skin grafts (FTSGs). Skin quality was objectively evaluated using MP6 noninvasive probes (Courage + Khazaka GmbH, Cologne, Germany), which measure melanin count, erythema, hydration, sebum, friction and transepidermal water loss. The results showed that there were no significant differences in melanin count, erythema, hydration, sebum level, friction value and transepidermal water loss (TEWL) between the site reconstructed with random local flaps and the same site on the healthy contralateral side of the face. However, both FTSGs and STSGs showed significantly higher levels in terms of TEWL and erythema, whereas the levels of hydration, sebum and friction were significantly lower compared to the healthy contralateral side. Moreover, STSGs resulted in a significant difference in melanin count. These findings imply that the complex pathophysiology of the wound-healing process possibly results in better skin-quality outcomes for random local flaps than skin autografts. Consequently, this suggests that random local flaps should be implemented whenever possible for the reconstruction of facial region defects. MDPI 2022-07-31 /pmc/articles/PMC9369767/ /pubmed/35956089 http://dx.doi.org/10.3390/jcm11154471 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Martinovic, Dinko
Lupi-Ferandin, Slaven
Tokic, Daria
Usljebrka, Mislav
Rados, Andrija
Pojatina, Ante
Kadic, Sanja
Puizina, Ema
Mihovilovic, Ante
Kumric, Marko
Vilovic, Marino
Leskur, Dario
Bozic, Josko
Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title_full Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title_fullStr Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title_full_unstemmed Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title_short Objective Skin Quality Assessment after Reconstructive Procedures for Facial Skin Defects
title_sort objective skin quality assessment after reconstructive procedures for facial skin defects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369767/
https://www.ncbi.nlm.nih.gov/pubmed/35956089
http://dx.doi.org/10.3390/jcm11154471
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