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An LSPR Sensor Integrated with VCSEL and Microfluidic Chip

The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end...

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Detalles Bibliográficos
Autores principales: Cao, Fang, Zhao, Xupeng, Lv, Xiaoqing, Hu, Liangchen, Jiang, Wenhui, Yang, Feng, Chi, Li, Chang, Pengying, Xu, Chen, Xie, Yiyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370176/
https://www.ncbi.nlm.nih.gov/pubmed/35957038
http://dx.doi.org/10.3390/nano12152607
Descripción
Sumario:The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end face. The sensitivity sensing test of the refractive index solution was realized, combined with microfluidic technology. At the same time, the finite-difference time- domain (FDTD) algorithm was applied to model and simulate the gold nanostructures. The experimental results showed that the output power of the sensor was related to the refractive index of the sucrose solution. The maximum sensitivity of the sensor was 1.65 × 10(6) nW/RIU, which gives it great application potential in the field of biomolecular detection.