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An LSPR Sensor Integrated with VCSEL and Microfluidic Chip
The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370176/ https://www.ncbi.nlm.nih.gov/pubmed/35957038 http://dx.doi.org/10.3390/nano12152607 |
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author | Cao, Fang Zhao, Xupeng Lv, Xiaoqing Hu, Liangchen Jiang, Wenhui Yang, Feng Chi, Li Chang, Pengying Xu, Chen Xie, Yiyang |
author_facet | Cao, Fang Zhao, Xupeng Lv, Xiaoqing Hu, Liangchen Jiang, Wenhui Yang, Feng Chi, Li Chang, Pengying Xu, Chen Xie, Yiyang |
author_sort | Cao, Fang |
collection | PubMed |
description | The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end face. The sensitivity sensing test of the refractive index solution was realized, combined with microfluidic technology. At the same time, the finite-difference time- domain (FDTD) algorithm was applied to model and simulate the gold nanostructures. The experimental results showed that the output power of the sensor was related to the refractive index of the sucrose solution. The maximum sensitivity of the sensor was 1.65 × 10(6) nW/RIU, which gives it great application potential in the field of biomolecular detection. |
format | Online Article Text |
id | pubmed-9370176 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93701762022-08-12 An LSPR Sensor Integrated with VCSEL and Microfluidic Chip Cao, Fang Zhao, Xupeng Lv, Xiaoqing Hu, Liangchen Jiang, Wenhui Yang, Feng Chi, Li Chang, Pengying Xu, Chen Xie, Yiyang Nanomaterials (Basel) Article The work introduces a localized surface plasmon resonance (LSPR) sensor chip integrated with vertical-cavity surface-emitting lasers (VCSELs). Using VCSEL as the light source, the hexagonal gold nanoparticle array was integrated with anodic aluminum oxide (AAO) as the mask on the light-emitting end face. The sensitivity sensing test of the refractive index solution was realized, combined with microfluidic technology. At the same time, the finite-difference time- domain (FDTD) algorithm was applied to model and simulate the gold nanostructures. The experimental results showed that the output power of the sensor was related to the refractive index of the sucrose solution. The maximum sensitivity of the sensor was 1.65 × 10(6) nW/RIU, which gives it great application potential in the field of biomolecular detection. MDPI 2022-07-29 /pmc/articles/PMC9370176/ /pubmed/35957038 http://dx.doi.org/10.3390/nano12152607 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Cao, Fang Zhao, Xupeng Lv, Xiaoqing Hu, Liangchen Jiang, Wenhui Yang, Feng Chi, Li Chang, Pengying Xu, Chen Xie, Yiyang An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title | An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title_full | An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title_fullStr | An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title_full_unstemmed | An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title_short | An LSPR Sensor Integrated with VCSEL and Microfluidic Chip |
title_sort | lspr sensor integrated with vcsel and microfluidic chip |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370176/ https://www.ncbi.nlm.nih.gov/pubmed/35957038 http://dx.doi.org/10.3390/nano12152607 |
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