The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia

Mesenchymal stem cells (MSCs) have made progress in the treatment of ischemic and inflammatory diseases. Preeclampsia (PE) is characterized by placenta ischemic and inflammatory injury. Our paper summarized the new role of MSCs in PE pathology and its potency in PE therapy and analyzed its current l...

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Detalles Bibliográficos
Autores principales: Jin, Sanshan, Wu, Canrong, Chen, Ming, Sun, Dongyan, Zhang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370554/
https://www.ncbi.nlm.nih.gov/pubmed/35966876
http://dx.doi.org/10.3389/fmed.2022.923334
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author Jin, Sanshan
Wu, Canrong
Chen, Ming
Sun, Dongyan
Zhang, Hua
author_facet Jin, Sanshan
Wu, Canrong
Chen, Ming
Sun, Dongyan
Zhang, Hua
author_sort Jin, Sanshan
collection PubMed
description Mesenchymal stem cells (MSCs) have made progress in the treatment of ischemic and inflammatory diseases. Preeclampsia (PE) is characterized by placenta ischemic and inflammatory injury. Our paper summarized the new role of MSCs in PE pathology and its potency in PE therapy and analyzed its current limitations. Intravenously administered MSCs dominantly distributed in perinatal tissues. There may be additional advantages to using MSCs-based therapies for reproductive disorders. It will provide new ideas for future research in this field.
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spelling pubmed-93705542022-08-12 The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia Jin, Sanshan Wu, Canrong Chen, Ming Sun, Dongyan Zhang, Hua Front Med (Lausanne) Medicine Mesenchymal stem cells (MSCs) have made progress in the treatment of ischemic and inflammatory diseases. Preeclampsia (PE) is characterized by placenta ischemic and inflammatory injury. Our paper summarized the new role of MSCs in PE pathology and its potency in PE therapy and analyzed its current limitations. Intravenously administered MSCs dominantly distributed in perinatal tissues. There may be additional advantages to using MSCs-based therapies for reproductive disorders. It will provide new ideas for future research in this field. Frontiers Media S.A. 2022-07-28 /pmc/articles/PMC9370554/ /pubmed/35966876 http://dx.doi.org/10.3389/fmed.2022.923334 Text en Copyright © 2022 Jin, Wu, Chen, Sun, Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Jin, Sanshan
Wu, Canrong
Chen, Ming
Sun, Dongyan
Zhang, Hua
The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title_full The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title_fullStr The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title_full_unstemmed The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title_short The pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
title_sort pathological and therapeutic roles of mesenchymal stem cells in preeclampsia
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370554/
https://www.ncbi.nlm.nih.gov/pubmed/35966876
http://dx.doi.org/10.3389/fmed.2022.923334
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