Design, Synthesis and Biological Evaluation of [1,2,4]Triazolo[1,5-a]pyrimidine Indole Derivatives against Gastric Cancer Cells MGC-803 via the Suppression of ERK Signaling Pathway

[1,2,4]Triazolo[1,5-a]pyrimidine and indole skeletons are widely used to design anticancer agents. Therefore, in this work, a series of [1,2,4]triazolo[1,5-a]pyrimidine indole derivatives were designed and synthesized by the molecular hybridization strategy. The antiproliferative activities of the t...

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Detalles Bibliográficos
Autores principales: Yu, Guang-Xi, Hu, Ying, Zhang, Wei-Xin, Tian, Xin-Yi, Zhang, Sai-Yang, Zhang, Yan, Yuan, Shuo, Song, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370682/
https://www.ncbi.nlm.nih.gov/pubmed/35956943
http://dx.doi.org/10.3390/molecules27154996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370682/
https://www.ncbi.nlm.nih.gov/pubmed/35956943
http://dx.doi.org/10.3390/molecules27154996

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