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Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study

To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in th...

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Autores principales: Sun, Yan, Supriya, Rashmi, Gao, Yang, Tao, Dan, Yu, Siyue, Wang, Aiwei, Chan, Hardaway Chun-Kwan, Ou, Xiaoting, Wang, Jingjing, Baker, Julien S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370698/
https://www.ncbi.nlm.nih.gov/pubmed/35956301
http://dx.doi.org/10.3390/nu14153127
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author Sun, Yan
Supriya, Rashmi
Gao, Yang
Tao, Dan
Yu, Siyue
Wang, Aiwei
Chan, Hardaway Chun-Kwan
Ou, Xiaoting
Wang, Jingjing
Baker, Julien S.
author_facet Sun, Yan
Supriya, Rashmi
Gao, Yang
Tao, Dan
Yu, Siyue
Wang, Aiwei
Chan, Hardaway Chun-Kwan
Ou, Xiaoting
Wang, Jingjing
Baker, Julien S.
author_sort Sun, Yan
collection PubMed
description To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population.
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spelling pubmed-93706982022-08-12 Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study Sun, Yan Supriya, Rashmi Gao, Yang Tao, Dan Yu, Siyue Wang, Aiwei Chan, Hardaway Chun-Kwan Ou, Xiaoting Wang, Jingjing Baker, Julien S. Nutrients Article To investigate the prevalence of hypertension and associated risk factors in Chinese children with intellectual disability, a cross-sectional study was conducted in a sample of 558 children with intellectual disability aged 6–18 years in Hong Kong, and 452 (81.0%) with valid data were included in the data analysis. Blood pressure was measured according to a standard protocol. Hypertension was defined using the age-, gender-, and height-specific classification criteria recommended by the 2018 Chinese Guidelines for Children. Multivariate and hierarchical logistic regression was fitted to examine the associations of hypertension with potential risk factors. Overall, 31.4% of the participants were classified as having hypertension. Obese children were more likely to develop hypertension than non-obese children (adjusted OR = 2.77, 95% CI: 1.28, 5.99, p = 0.010). A paternal education of college or above and a paternal occupation of clerks, sales representatives, and workers were also associated with an increased risk of hypertension. The prevalence of hypertension is high among Chinese children with intellectual disability. Obesity was the strongest risk factor. Further longitudinal studies are warranted to confirm our findings. Nevertheless, preventions against obesity are promising to receive doubled benefits in reducing both obesity and hypertension, given its strong relationship with hypertension in this special population. MDPI 2022-07-29 /pmc/articles/PMC9370698/ /pubmed/35956301 http://dx.doi.org/10.3390/nu14153127 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Sun, Yan
Supriya, Rashmi
Gao, Yang
Tao, Dan
Yu, Siyue
Wang, Aiwei
Chan, Hardaway Chun-Kwan
Ou, Xiaoting
Wang, Jingjing
Baker, Julien S.
Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title_full Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title_fullStr Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title_full_unstemmed Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title_short Hypertension and Associated Risk Factors among Children with Intellectual Disability: A Cross-Sectional Study
title_sort hypertension and associated risk factors among children with intellectual disability: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370698/
https://www.ncbi.nlm.nih.gov/pubmed/35956301
http://dx.doi.org/10.3390/nu14153127
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