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Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

Elucidation of physicochemical mechanisms of enzymatic processes is one of the main tasks of modern biology. High efficiency and selectivity of enzymatic catalysis are mostly ensured by conformational dynamics of enzymes and substrates. Here, we applied a stopped-flow kinetic analysis based on fluor...

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Detalles Bibliográficos
Autores principales:	Kanazhevskaya, Lyubov Yu., Smyshliaev, Denis A., Timofeyeva, Nadezhda A., Ishchenko, Alexander A., Saparbaev, Murat, Kuznetsov, Nikita A., Fedorova, Olga S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9370705/ https://www.ncbi.nlm.nih.gov/pubmed/35956910 http://dx.doi.org/10.3390/molecules27154960

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