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Amyloid pathology disrupts gliotransmitter release in astrocytes
Accumulation of amyloid-beta (Aβ) is associated with synaptic dysfunction and destabilization of astrocytic calcium homeostasis. A growing body of evidence support astrocytes as active modulators of synaptic transmission via calcium-mediated gliotransmission. However, the details of mechanisms linki...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371304/ https://www.ncbi.nlm.nih.gov/pubmed/35913987 http://dx.doi.org/10.1371/journal.pcbi.1010334 |