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Critical examination of Ptbp1-mediated glia-to-neuron conversion in the mouse retina
Reprogramming glial cells to convert them into neurons represents a potential therapeutic strategy that could repair damaged neural circuits and restore function. Recent studies show that downregulation of the RNA-binding protein PTBP1 leads to one-step conversion of Müller glia (MG) into retinal ga...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371382/ https://www.ncbi.nlm.nih.gov/pubmed/35705044 http://dx.doi.org/10.1016/j.celrep.2022.110960 |