Cargando…
Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin
Endoscopic resection is an effective treatment for subepithelial tumors arising from the muscularis propria layer of the stomach. However, the invasion pattern revealed by the pathological examination of tumor specimens is often not consistent with the findings of preprocedural endoscopic ultrasound...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371510/ https://www.ncbi.nlm.nih.gov/pubmed/35960061 http://dx.doi.org/10.1097/MD.0000000000029947 |
_version_ | 1784767161338691584 |
---|---|
author | Cho, Jinwoong Han, Jihyun Choi, Mirim Song, Jaesun Yang, Mina Lee, Youngjae |
author_facet | Cho, Jinwoong Han, Jihyun Choi, Mirim Song, Jaesun Yang, Mina Lee, Youngjae |
author_sort | Cho, Jinwoong |
collection | PubMed |
description | Endoscopic resection is an effective treatment for subepithelial tumors arising from the muscularis propria layer of the stomach. However, the invasion pattern revealed by the pathological examination of tumor specimens is often not consistent with the findings of preprocedural endoscopic ultrasounds (EUS). We compared the real growing patterns of tumors, as evaluated on histopathological examination, with their EUS images, and analyzed the outcomes of endoscopic resections in relation to the EUS findings. From January 2006 to June 2015, 32 patients underwent endoscopic resection for gastric tumors originating from the muscularis propria at our hospital. We divided the patients into 3 groups according to the location of the tumor as diagnosed using pre procedural EUS: submucosa (group I, n = 5), muscularis propria (group II, n = 14), and tumors extending into the outer cavity (group III, n = 13). Histopathological examination revealed 15 patients with gastrointestinal stromal tumors (GISTs), 14 with leiomyomas, and 3 with schwannomas. Accuracy of EUS in evaluating tumor invasion was 56%. Some tumors in groups I and II was removed by endoscopic submucosal dissection only. Muscular dissection was needed in 10 patients (71%) in group II and 9 patients (69%) in group III. Four patients (31%) in group III were found to have subserosal tumors. The complete resection rate was 88% (23 patients) among patients who underwent endoscopic submucosal dissection and endoscopic muscular dissection, and 67% (4 patients) among patients who underwent endoscopic subserosal dissection (ESSD). The tumor was completely removed in 12 patients (86%) in group II and 10 patients (77%) in group III. EUS accurately predicts the layer of the subepithelial tumor in the stomach; however, the pattern of invasion of surrounding structures is difficult to evaluate using EUS. |
format | Online Article Text |
id | pubmed-9371510 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-93715102022-08-16 Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin Cho, Jinwoong Han, Jihyun Choi, Mirim Song, Jaesun Yang, Mina Lee, Youngjae Medicine (Baltimore) Research Article Endoscopic resection is an effective treatment for subepithelial tumors arising from the muscularis propria layer of the stomach. However, the invasion pattern revealed by the pathological examination of tumor specimens is often not consistent with the findings of preprocedural endoscopic ultrasounds (EUS). We compared the real growing patterns of tumors, as evaluated on histopathological examination, with their EUS images, and analyzed the outcomes of endoscopic resections in relation to the EUS findings. From January 2006 to June 2015, 32 patients underwent endoscopic resection for gastric tumors originating from the muscularis propria at our hospital. We divided the patients into 3 groups according to the location of the tumor as diagnosed using pre procedural EUS: submucosa (group I, n = 5), muscularis propria (group II, n = 14), and tumors extending into the outer cavity (group III, n = 13). Histopathological examination revealed 15 patients with gastrointestinal stromal tumors (GISTs), 14 with leiomyomas, and 3 with schwannomas. Accuracy of EUS in evaluating tumor invasion was 56%. Some tumors in groups I and II was removed by endoscopic submucosal dissection only. Muscular dissection was needed in 10 patients (71%) in group II and 9 patients (69%) in group III. Four patients (31%) in group III were found to have subserosal tumors. The complete resection rate was 88% (23 patients) among patients who underwent endoscopic submucosal dissection and endoscopic muscular dissection, and 67% (4 patients) among patients who underwent endoscopic subserosal dissection (ESSD). The tumor was completely removed in 12 patients (86%) in group II and 10 patients (77%) in group III. EUS accurately predicts the layer of the subepithelial tumor in the stomach; however, the pattern of invasion of surrounding structures is difficult to evaluate using EUS. Lippincott Williams & Wilkins 2022-08-12 /pmc/articles/PMC9371510/ /pubmed/35960061 http://dx.doi.org/10.1097/MD.0000000000029947 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. |
spellingShingle | Research Article Cho, Jinwoong Han, Jihyun Choi, Mirim Song, Jaesun Yang, Mina Lee, Youngjae Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title | Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title_full | Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title_fullStr | Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title_full_unstemmed | Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title_short | Correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
title_sort | correlation between endoscopic resection outcomes and endosonographic findings in gastric tumors with muscularis propria origin |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371510/ https://www.ncbi.nlm.nih.gov/pubmed/35960061 http://dx.doi.org/10.1097/MD.0000000000029947 |
work_keys_str_mv | AT chojinwoong correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin AT hanjihyun correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin AT choimirim correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin AT songjaesun correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin AT yangmina correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin AT leeyoungjae correlationbetweenendoscopicresectionoutcomesandendosonographicfindingsingastrictumorswithmuscularispropriaorigin |