Cargando…

The Role of NR4A1 in the Pathophysiology of Osteosarcoma: A Comprehensive Bioinformatics Analysis of the Single-Cell RNA Sequencing Dataset

Osteosarcoma is a kind of aggressive human malignancy, and the prognosis of the patients with osteosarcoma remains low. Studies have demonstrated that the tumor microenvironment plays a key role in regulating osteosarcoma progression. Recent studies have also shown that scRNA-seq plays an essential...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Weidong, Hao, Yuedong, Tian, Xiao, Jiang, Jing, Qiu, Quanhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371594/ https://www.ncbi.nlm.nih.gov/pubmed/35965537 http://dx.doi.org/10.3389/fonc.2022.879288

Ejemplares similares

Corrigendum: The role of NR4A1 in the pathophysiology of osteosarcoma: A comprehensive bioinformatics analysis of the single-cell RNA sequencing dataset
por: Liu, Weidong, et al.
Publicado: (2022)

Identification of Cell Subpopulations and Interactive Signaling Pathways From a Single-Cell RNA Sequencing Dataset in Osteosarcoma: A Comprehensive Bioinformatics Analysis
por: Wu, Rong, et al.
Publicado: (2022)

LncRNA NR_027471 Functions as a ceRNA for miRNA-8055 Leading to Suppression of Osteosarcoma by Regulating the Expression of TP53INP1
por: Chen, Jiajia, et al.
Publicado: (2020)

Novel Non-Coding Transcript in NR4A3 Locus, LncNR4A3, Regulates RNA Processing Machinery Proteins and NR4A3 Expression
por: Congrains, Ada, et al.
Publicado: (2020)

High GNG4 predicts adverse prognosis for osteosarcoma: Bioinformatics prediction and experimental verification
por: Jiang, Xiaohong, et al.
Publicado: (2023)

The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma
por: Feng, Haijun, et al.
Publicado: (2023)

Identification of Hub Genes Associated With Melanoma Development by Comprehensive Bioinformatics Analysis
por: Jiang, Jie, et al.
Publicado: (2021)

Identification of Potential Therapeutic Targets and Immune Cell Infiltration Characteristics in Osteosarcoma Using Bioinformatics Strategy
por: Niu, Jianfang, et al.
Publicado: (2020)

Development of a Chemoresistant Risk Scoring Model for Prechemotherapy Osteosarcoma Using Single-Cell Sequencing
por: Zeng, Ziliang, et al.
Publicado: (2022)

NR4A Family Genes: A Review of Comprehensive Prognostic and Gene Expression Profile Analysis in Breast Cancer
por: Yousefi, Hassan, et al.
Publicado: (2022)

Comprehensive Analysis of a Ferroptosis-Related lncRNA Signature for Predicting Prognosis and Immune Landscape in Osteosarcoma
por: Zhang, Yiming, et al.
Publicado: (2022)

Identifying Long Non-coding RNA of Prostate Cancer Associated With Radioresponse by Comprehensive Bioinformatics Analysis
por: Xu, Meng, et al.
Publicado: (2020)

To Explore the Mechanism of the GRM4 Gene in Osteosarcoma by RNA Sequencing and Bioinformatics Approach
por: Pang, Yunguo, et al.
Publicado: (2018)

Comprehensive Review of Web Servers and Bioinformatics Tools for Cancer Prognosis Analysis
por: Zheng, Hong, et al.
Publicado: (2020)

Current Challenges in the Bioinformatics of Single Cell Genomics
por: Ning, Luwen, et al.
Publicado: (2014)

Unveiling novel insights in prostate cancer through single-cell RNA sequencing
por: Yu, Wenyue, et al.
Publicado: (2023)

The Role of COL5A2 in Patients With Muscle-Invasive Bladder Cancer: A Bioinformatics Analysis of Public Datasets Involving 787 Subjects and 29 Cell Lines
por: Meng, Xiang-Yu, et al.
Publicado: (2019)

Differential expression and bioinformatics analysis of circRNA in osteosarcoma
por: Xi, Yizhe, et al.
Publicado: (2019)

Therapeutic potential of NR4A1 in cancer: Focus on metabolism
por: Deng, Shan, et al.
Publicado: (2022)

Recent Advances in Nanoplatforms for the Treatment of Osteosarcoma
por: Wu, Kunzhe, et al.
Publicado: (2022)

Therapeutic Potential of Circular RNAs in Osteosarcoma
por: Wan, Ben, et al.
Publicado: (2020)

Novel Therapeutic Savior for Osteosarcoma: The Endorsement of Ferroptosis
por: Qiu, Cheng, et al.
Publicado: (2022)

Osteosarcoma and Metastasis
por: Sheng, Gaohong, et al.
Publicado: (2021)

The expression characteristics of transmembrane protein genes in pancreatic ductal adenocarcinoma through comprehensive analysis of bulk and single-cell RNA sequence
por: Ye, Chen, et al.
Publicado: (2023)

Comprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay
por: Medvedev, Alexander, et al.
Publicado: (2022)

The role of tumor-associated macrophages in glioma cohort: through both traditional RNA sequencing and single cell RNA sequencing
por: Hou, Yunan, et al.
Publicado: (2023)

The intervention effect of Aitongxiao prescription on primary liver cancer rats was evaluated based on high-throughput miRNA sequencing and bioinformatics analysis
por: Xu, Lijing, et al.
Publicado: (2023)

Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma
por: Liu, Yun, et al.
Publicado: (2021)

New Prognostic Biomarkers and Drug Targets for Skin Cutaneous Melanoma via Comprehensive Bioinformatic Analysis and Validation
por: Zhou, Sitong, et al.
Publicado: (2021)

KIF21B Expression in Osteosarcoma and Its Regulatory Effect on Osteosarcoma Cell Proliferation and Apoptosis Through the PI3K/AKT Pathway
por: Ni, Songjia, et al.
Publicado: (2021)

Comprehensive analysis of fatty acid and lactate metabolism–related genes for prognosis value, immune infiltration, and therapy in osteosarcoma patients
por: Wu, Zhouwei, et al.
Publicado: (2022)

Exosomal Long Non-Coding RNA ANCR Mediates Drug Resistance in Osteosarcoma
por: Hu, Xin, et al.
Publicado: (2022)

Aggrephagy-related patterns in tumor microenvironment, prognosis, and immunotherapy for acute myeloid leukemia: a comprehensive single-cell RNA sequencing analysis
por: Pan, Yan, et al.
Publicado: (2023)

Identification and validation of an anoikis-related lncRNA signature to predict prognosis and immune landscape in osteosarcoma
por: Zhang, Jun-Song, et al.
Publicado: (2023)

Silencing circOMA1 Inhibits Osteosarcoma Progression by Sponging miR-1294 to Regulate c-Myc Expression
por: Shi, Yubo, et al.
Publicado: (2022)

Corrigendum: Single-cell transcriptomics reveals the complexity of the tumor microenvironment of treatment-naive osteosarcoma
por: Liu, Yun, et al.
Publicado: (2022)

Draft Genome Sequences of Marine Flavobacterium Nonlabens Strains NR17, NR24, NR27, NR32, NR33, and Ara13
por: Nakanishi, Masato, et al.
Publicado: (2014)

Identifying Immune Cell Infiltration and Effective Diagnostic Biomarkers in Lung Adenocarcinoma by Comprehensive Bioinformatics Analysis and In Vitro Study
por: Li, Xinyan, et al.
Publicado: (2022)

Animal Models in Osteosarcoma
por: Guijarro, Maria V., et al.
Publicado: (2014)

Novel Immunotherapies for Osteosarcoma
por: Lu, Yubao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9bdbvugvhfr9jinmu8li6pcs9m