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ProbeTools: designing hybridization probes for targeted genomic sequencing of diverse and hypervariable viral taxa

BACKGROUND: Sequencing viruses in many specimens is hindered by excessive background material from hosts, microbiota, and environmental organisms. Consequently, enrichment of target genomic material is necessary for practical high-throughput viral genome sequencing. Hybridization probes are widely u...

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Detalles Bibliográficos
Autores principales: Kuchinski, Kevin S., Duan, Jun, Himsworth, Chelsea, Hsiao, William, Prystajecky, Natalie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371634/
https://www.ncbi.nlm.nih.gov/pubmed/35953803
http://dx.doi.org/10.1186/s12864-022-08790-4