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The duper mutation reveals previously unsuspected functions of Cryptochrome 1 in circadian entrainment and heart disease
The Cryptochrome 1 (Cry1)–deficient duper mutant hamster has a short free-running period in constant darkness (τ(DD)) and shows large phase shifts in response to brief light pulses. We tested whether this measure of the lability of the circadian phase is a general characteristic of Cry1-null animals...
Autores principales: | Sisson, Chip, Bahiru, Michael Seifu, Manoogian, Emily N. C., Bittman, Eric L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371649/ https://www.ncbi.nlm.nih.gov/pubmed/35930669 http://dx.doi.org/10.1073/pnas.2121883119 |
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