Protective anti-gB neutralizing antibodies targeting two vulnerable sites for EBV-cell membrane fusion

Epstein-Barr virus (EBV) infects more than 90% of the world’s adult population and accounts for a significant cancer burden of epithelial and B cell origins. Glycoprotein B (gB) is the primary fusogen essential for EBV entry into host cells. Here, we isolated two EBV gB-specific neutralizing antibod...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao, Hong, Junping, Zhong, Ling, Wu, Qian, Zhang, Shanshan, Zhu, Qianying, Chen, Haiwen, Wei, Dongmei, Li, Rui, Zhang, Wanlin, Zhang, Xinyu, Wang, Guosong, Zhou, Xiang, Chen, Junyu, Kang, Yinfeng, Zha, Zhenghui, Duan, Xiaobing, Huang, Yang, Sun, Cong, Kong, Xiangwei, Zhou, Yan, Chen, Yanhong, Ye, Xiaoping, Feng, Qisheng, Li, Shaowei, Xiang, Tong, Gao, Song, Zeng, Mu-Sheng, Zheng, Qingbing, Chen, Yixin, Zeng, Yi-Xin, Xia, Ningshao, Xu, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371650/
https://www.ncbi.nlm.nih.gov/pubmed/35917353
http://dx.doi.org/10.1073/pnas.2202371119

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