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Unexpected role for IGF-1 in starvation: Maintenance of blood glucose

Wild-type (WT) mice maintain viable levels of blood glucose even when adipose stores are depleted by 6 d of 60% calorie restriction followed by a 23-h fast (hereafter designated as “starved” mice). Survival depends on ghrelin, an octanoylated peptide hormone. Mice that lack ghrelin suffer lethal hyp...

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Detalles Bibliográficos
Autores principales: Fang, Fei, Goldstein, Joseph L., Shi, Xuanming, Liang, Guosheng, Brown, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371671/
https://www.ncbi.nlm.nih.gov/pubmed/35914126
http://dx.doi.org/10.1073/pnas.2208855119