P38α MAPK is a gatekeeper of uterine progesterone responsiveness at peri-implantation via Ube3c-mediated PGR degradation

Estrogen and progesterone specify the establishment of uterine receptivity mainly through their respective nuclear receptors, ER and PR. PR is transcriptionally induced by estrogen–ER signaling in the endometrium, but how the protein homeostasis of PR in the endometrium is regulated remains elusive....

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Detalles Bibliográficos
Autores principales: Tang, Yedong, Qiu, Jingtao, Tang, Zhenzhou, Li, Gaizhen, Gu, Mengqing, Wang, Yang, Bao, Haili, Deng, Wenbo, Lu, Zhongxian, Otsu, Kinya, Wang, Zhengchao, Wang, Haibin, Kong, Shuangbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371708/
https://www.ncbi.nlm.nih.gov/pubmed/35914132
http://dx.doi.org/10.1073/pnas.2206000119

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