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Widespread hydroxylation of unstructured lysine-rich protein domains by JMJD6
The Jumonji domain–containing protein JMJD6 is a 2-oxoglutarate–dependent dioxygenase associated with a broad range of biological functions. Cellular studies have implicated the enzyme in chromatin biology, transcription, DNA repair, mRNA splicing, and cotranscriptional processing. Although not all...
Autores principales: | Cockman, Matthew E., Sugimoto, Yoichiro, Pegg, Hamish B., Masson, Norma, Salah, Eidarus, Tumber, Anthony, Flynn, Helen R., Kirkpatrick, Joanna M., Schofield, Christopher J., Ratcliffe, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371714/ https://www.ncbi.nlm.nih.gov/pubmed/35930668 http://dx.doi.org/10.1073/pnas.2201483119 |
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