Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity

Histone variants, which can be expressed outside of S-phase and deposited DNA synthesis-independently, provide long-term histone replacement in postmitotic cells, including neurons. Beyond replenishment, histone variants also play active roles in gene regulation by modulating chromatin states or ena...

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Detalles Bibliográficos
Autores principales: Funk, Owen H., Qalieh, Yaman, Doyle, Daniel Z., Lam, Mandy M., Kwan, Kenneth Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371731/
https://www.ncbi.nlm.nih.gov/pubmed/35930666
http://dx.doi.org/10.1073/pnas.2116956119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371731/
https://www.ncbi.nlm.nih.gov/pubmed/35930666
http://dx.doi.org/10.1073/pnas.2116956119

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