Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1(D173A) mice

DNA damage response pathways rely extensively on nuclease activity to process DNA intermediates. Exonuclease 1 (EXO1) is a pleiotropic evolutionary conserved DNA exonuclease involved in various DNA repair pathways, replication, antibody diversification, and meiosis. But, whether EXO1 facilitates the...

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Detalles Bibliográficos
Autores principales: Wang, Shanzhi, Lee, Kyeryoung, Gray, Stephen, Zhang, Yongwei, Tang, Catherine, Morrish, Rikke B, Tosti, Elena, van Oers, Johanna, Amin, Mohammad Ruhul, Cohen, Paula E, MacCarthy, Thomas, Roa, Sergio, Scharff, Matthew D, Edelmann, Winfried, Chahwan, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371890/
https://www.ncbi.nlm.nih.gov/pubmed/35849338
http://dx.doi.org/10.1093/nar/gkac616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371890/
https://www.ncbi.nlm.nih.gov/pubmed/35849338
http://dx.doi.org/10.1093/nar/gkac616

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