LncRNA CTBP1-DT-encoded microprotein DDUP sustains DNA damage response signalling to trigger dual DNA repair mechanisms

Sustaining DNA damage response (DDR) signalling via retention of DDR factors at damaged sites is important for transmitting damage-sensing and repair signals. Herein, we found that DNA damage provoked the association of ribosomes with IRES region in lncRNA CTBP1-DT, which overcame the negative effec...

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Detalles Bibliográficos
Autores principales: Yu, Ruyuan, Hu, Yameng, Zhang, Shuxia, Li, Xincheng, Tang, Miaoling, Yang, Meisongzhu, Wu, Xingui, Li, Ziwen, Liao, Xinyi, Xu, Yingru, Li, Man, Chen, Suwen, Qian, Wanying, Gong, Li-Yun, Song, Libing, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371908/
https://www.ncbi.nlm.nih.gov/pubmed/35849344
http://dx.doi.org/10.1093/nar/gkac611

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