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Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care

We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART,...

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Autores principales: Zanoni, Brian C., Musinguzi, Nicholas, Archary, Moherndran, Sibaya, Thobekile, Haberer, Jessica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372012/
https://www.ncbi.nlm.nih.gov/pubmed/35362907
http://dx.doi.org/10.1007/s10461-022-03650-4
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author Zanoni, Brian C.
Musinguzi, Nicholas
Archary, Moherndran
Sibaya, Thobekile
Haberer, Jessica E.
author_facet Zanoni, Brian C.
Musinguzi, Nicholas
Archary, Moherndran
Sibaya, Thobekile
Haberer, Jessica E.
author_sort Zanoni, Brian C.
collection PubMed
description We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART, with documented HIV status disclosure, and higher rating on the HIV Adolescent Readiness to Transition Scale had significantly higher odds of viral suppression after transition. Conversely, females, those with older age at ART initiation, and those with prior alcohol use had significantly lower odds of viral suppression after transition. Using these data, we created a transition readiness score organized into low, intermediate, and high levels of transition readiness. This transition readiness score can be used to identify adolescents who are likely ready to transition to adult care and identify additional areas for intervention to improve the likelihood of successful transition for those with lower transition readiness scores.
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spelling pubmed-93720122022-08-13 Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care Zanoni, Brian C. Musinguzi, Nicholas Archary, Moherndran Sibaya, Thobekile Haberer, Jessica E. AIDS Behav Original Paper We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART, with documented HIV status disclosure, and higher rating on the HIV Adolescent Readiness to Transition Scale had significantly higher odds of viral suppression after transition. Conversely, females, those with older age at ART initiation, and those with prior alcohol use had significantly lower odds of viral suppression after transition. Using these data, we created a transition readiness score organized into low, intermediate, and high levels of transition readiness. This transition readiness score can be used to identify adolescents who are likely ready to transition to adult care and identify additional areas for intervention to improve the likelihood of successful transition for those with lower transition readiness scores. Springer US 2022-04-01 2022 /pmc/articles/PMC9372012/ /pubmed/35362907 http://dx.doi.org/10.1007/s10461-022-03650-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Paper
Zanoni, Brian C.
Musinguzi, Nicholas
Archary, Moherndran
Sibaya, Thobekile
Haberer, Jessica E.
Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title_full Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title_fullStr Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title_full_unstemmed Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title_short Development of a transition readiness score for adolescents living with perinatally-acquired HIV and transitioning to adult care
title_sort development of a transition readiness score for adolescents living with perinatally-acquired hiv and transitioning to adult care
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372012/
https://www.ncbi.nlm.nih.gov/pubmed/35362907
http://dx.doi.org/10.1007/s10461-022-03650-4
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