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Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells

Blood–brain barrier (BBB) integrity is necessary to maintain homeostasis of the central nervous system (CNS). NMDA receptor (NMDAR) function and expression have been implicated in BBB integrity. However, as evidenced in neuroinflammatory conditions, BBB disruption contributes to immune cell infiltra...

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Detalles Bibliográficos
Autores principales: Epping, Lisa, Schroeter, Christina B., Nelke, Christopher, Bock, Stefanie, Gola, Lukas, Ritter, Nadine, Herrmann, Alexander M., Räuber, Saskia, Henes, Antonia, Wasser, Beatrice, Fernandez-Orth, Juncal, Neuhaus, Winfried, Bittner, Stefan, Budde, Thomas, Platten, Michael, Kovac, Stjepana, Seebohm, Guiscard, Ruck, Tobias, Cerina, Manuela, Meuth, Sven G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372018/
https://www.ncbi.nlm.nih.gov/pubmed/35951110
http://dx.doi.org/10.1007/s00018-022-04502-z

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