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Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells
Blood–brain barrier (BBB) integrity is necessary to maintain homeostasis of the central nervous system (CNS). NMDA receptor (NMDAR) function and expression have been implicated in BBB integrity. However, as evidenced in neuroinflammatory conditions, BBB disruption contributes to immune cell infiltra...
Autores principales: | Epping, Lisa, Schroeter, Christina B., Nelke, Christopher, Bock, Stefanie, Gola, Lukas, Ritter, Nadine, Herrmann, Alexander M., Räuber, Saskia, Henes, Antonia, Wasser, Beatrice, Fernandez-Orth, Juncal, Neuhaus, Winfried, Bittner, Stefan, Budde, Thomas, Platten, Michael, Kovac, Stjepana, Seebohm, Guiscard, Ruck, Tobias, Cerina, Manuela, Meuth, Sven G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372018/ https://www.ncbi.nlm.nih.gov/pubmed/35951110 http://dx.doi.org/10.1007/s00018-022-04502-z |
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