Ammonium metavanadate (NH(4)VO(3)): a highly efficient and eco-friendly catalyst for one-pot synthesis of pyridines and 1,4-dihydropyridines

In this study, we reported the ammonium metavanadate (NH(4)VO(3)) as an efficient, cost-effective, and mild catalyst for the synthesis of substituted pyridines via a one-pot pseudo four-component reaction. Furthermore, we investigated Hantzsch 1,4-dihydropyridines (1,4-DHPs) synthesis and oxidation...

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Detalles Bibliográficos
Autores principales: Rahimi, Jamal, Niksefat, Maryam, Heidari, Marzieh, Naderi, Mehdi, Abbasi, Hadis, Tajik Ijdani, Mohammad, Maleki, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372032/
https://www.ncbi.nlm.nih.gov/pubmed/35953520
http://dx.doi.org/10.1038/s41598-022-17378-7
Descripción
Sumario:In this study, we reported the ammonium metavanadate (NH(4)VO(3)) as an efficient, cost-effective, and mild catalyst for the synthesis of substituted pyridines via a one-pot pseudo four-component reaction. Furthermore, we investigated Hantzsch 1,4-dihydropyridines (1,4-DHPs) synthesis and oxidation of 1,4-DHPs to their corresponding pyridines. The present approach offers a rapid methodology for accessing various pyridines with broad functional group tolerance and good yields using NH(4)VO(3) catalyst as a green catalyst.

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