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TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes

The Ten-eleven translocation (TET) family of dioxygenases mediate cytosine demethylation by catalyzing the oxidation of 5-methylcytosine (5mC). TET-mediated DNA demethylation controls the proper differentiation of embryonic stem cells and TET members display functional redundancy during early gastru...

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Detalles Bibliográficos
Autores principales:	Wang, Lijun, You, Xiuling, Ruan, Dengfeng, Shao, Rui, Dai, Hai-Qiang, Shen, Weiliang, Xu, Guo-Liang, Liu, Wanlu, Zou, Weiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372040/ https://www.ncbi.nlm.nih.gov/pubmed/35953487 http://dx.doi.org/10.1038/s41467-022-32138-x

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