The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization

Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of genetic liability for AD in 334,968 participants of the UK Biobank study, stratified by age. We also examined the effects of AD genetic liabil...

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Detalles Bibliográficos
Autores principales: Korologou-Linden, Roxanna, Bhatta, Laxmi, Brumpton, Ben M., Howe, Laura D., Millard, Louise A. C., Kolaric, Katarina, Ben-Shlomo, Yoav, Williams, Dylan M., Smith, George Davey, Anderson, Emma L., Stergiakouli, Evie, Davies, Neil M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372151/
https://www.ncbi.nlm.nih.gov/pubmed/35953482
http://dx.doi.org/10.1038/s41467-022-32183-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372151/
https://www.ncbi.nlm.nih.gov/pubmed/35953482
http://dx.doi.org/10.1038/s41467-022-32183-6

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