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The causes and consequences of Alzheimer’s disease: phenome-wide evidence from Mendelian randomization
Alzheimer’s disease (AD) has no proven causal and modifiable risk factors, or effective interventions. We report a phenome-wide association study (PheWAS) of genetic liability for AD in 334,968 participants of the UK Biobank study, stratified by age. We also examined the effects of AD genetic liabil...
Autores principales: | Korologou-Linden, Roxanna, Bhatta, Laxmi, Brumpton, Ben M., Howe, Laura D., Millard, Louise A. C., Kolaric, Katarina, Ben-Shlomo, Yoav, Williams, Dylan M., Smith, George Davey, Anderson, Emma L., Stergiakouli, Evie, Davies, Neil M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372151/ https://www.ncbi.nlm.nih.gov/pubmed/35953482 http://dx.doi.org/10.1038/s41467-022-32183-6 |
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