Growth of T-cell lymphoma cells is inhibited by mPGES-1/PGE2 suppression via JAK/STAT, TGF-β/Smad3 and PI3K/AKT signal pathways

BACKGROUND: T-cell lymphoma (TCL) has a very poor prognosis with limited treatment options and novel therapeutic target is urgently needed. Our previous studies have found that suppression of membrane-bound prostaglandin E2 synthase l/prostaglandin E2 (mPGES-1/PGE2) exerted anti-neoplastic effects i...

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Detalles Bibliográficos
Autores principales: Li, Yiqing, Qiu, Meng, Li, Boqi, Xiao, Jie, Yang, Wenjuan, Xie, Shuangfeng, Du, Yumo, Huang, Kezhi, Nie, Danian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372224/
https://www.ncbi.nlm.nih.gov/pubmed/35966330
http://dx.doi.org/10.21037/tcr-21-2834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372224/
https://www.ncbi.nlm.nih.gov/pubmed/35966330
http://dx.doi.org/10.21037/tcr-21-2834

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