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Ryanodine receptor (RYR) mutational status correlates with tumor mutational burden, age and smoking status and stratifies non-small cell lung cancer patient prognosis

BACKGROUND: The ryanodine receptors (RYRs) have been implicated in many muscular, cardiac and neurological diseases. However, there are almost no studies so far focusing on RYR genetic alterations and its roles in cancer, especially in non-small cell lung cancer (NSCLC). METHODS: The whole-exome seq...

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Detalles Bibliográficos
Autores principales:	Wang, Yang, Chen, Yun, Zhang, Libin, Xiong, Jian, Xu, Lele, Cheng, Changfu, Xu, Zheyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372243/ https://www.ncbi.nlm.nih.gov/pubmed/35966320 http://dx.doi.org/10.21037/tcr-21-2395

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