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Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess

The use of poloxamer 407 gels have been reported in several studies to prolong the release of drugs at the injection site. Oral lesions unrelated to dental disease are rare but may result in ulceration and sequestration of bone. To date, there have been no reports on the use of penicillin G potassiu...

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Autores principales: Larsen, Elizabeth A., Lack, Amy C., Wassack, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372548/
https://www.ncbi.nlm.nih.gov/pubmed/35968007
http://dx.doi.org/10.3389/fvets.2022.783753
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author Larsen, Elizabeth A.
Lack, Amy C.
Wassack, Erica
author_facet Larsen, Elizabeth A.
Lack, Amy C.
Wassack, Erica
author_sort Larsen, Elizabeth A.
collection PubMed
description The use of poloxamer 407 gels have been reported in several studies to prolong the release of drugs at the injection site. Oral lesions unrelated to dental disease are rare but may result in ulceration and sequestration of bone. To date, there have been no reports on the use of penicillin G potassium poloxamer 407 gel and its effect on wound healing. The present case report describes the use of a penicillin G potassium poloxamer 407 gel for the treatment of a sublingual abscess involving the mandible in a 20 year old Arabian mare who initially presented with acute onset of dysphagia, hypersalivation, and a mass under the tongue. A presumptive diagnosis of lingual cellulitis was made, and a sublingual abscess ruptured on day 7 of hospitalization. In this case, poloxamer 407 gel was used to decrease wound contamination, protect the exposed mandible, and potentially prolong the release of penicillin G potassium into the wound.
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spelling pubmed-93725482022-08-13 Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess Larsen, Elizabeth A. Lack, Amy C. Wassack, Erica Front Vet Sci Veterinary Science The use of poloxamer 407 gels have been reported in several studies to prolong the release of drugs at the injection site. Oral lesions unrelated to dental disease are rare but may result in ulceration and sequestration of bone. To date, there have been no reports on the use of penicillin G potassium poloxamer 407 gel and its effect on wound healing. The present case report describes the use of a penicillin G potassium poloxamer 407 gel for the treatment of a sublingual abscess involving the mandible in a 20 year old Arabian mare who initially presented with acute onset of dysphagia, hypersalivation, and a mass under the tongue. A presumptive diagnosis of lingual cellulitis was made, and a sublingual abscess ruptured on day 7 of hospitalization. In this case, poloxamer 407 gel was used to decrease wound contamination, protect the exposed mandible, and potentially prolong the release of penicillin G potassium into the wound. Frontiers Media S.A. 2022-07-29 /pmc/articles/PMC9372548/ /pubmed/35968007 http://dx.doi.org/10.3389/fvets.2022.783753 Text en Copyright © 2022 Larsen, Lack and Wassack. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Larsen, Elizabeth A.
Lack, Amy C.
Wassack, Erica
Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title_full Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title_fullStr Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title_full_unstemmed Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title_short Case report: Use of penicillin G potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
title_sort case report: use of penicillin g potassium in poloxamer 407 gel to aid in healing of an equine sublingual abscess
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372548/
https://www.ncbi.nlm.nih.gov/pubmed/35968007
http://dx.doi.org/10.3389/fvets.2022.783753
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