Combination of 4-1BB and DAP10 promotes proliferation and persistence of NKG2D(bbz) CAR-T cells

Chimeric antigen receptor (CAR)-T cell therapy has been shown to have considerable therapeutic effects in hematological malignancies, and NKG2D(z) CAR-T cell therapy has been verified to be safe based on clinical trials. However, due to the poor persistence of NKG2D(z) CAR-T cells, their therapeutic...

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Detalles Bibliográficos
Autores principales: Wei, Cheng, Xia, Kangfu, Xie, Yucheng, Ye, Sishi, Ding, Yanghui, Liu, Zairu, Zheng, Rong, Long, Jing, Wei, Qinchuan, Li, Yumei, Yang, Dongxia, Xu, Xiaojun, Zhao, Ai, Gao, Jimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372572/
https://www.ncbi.nlm.nih.gov/pubmed/35965586
http://dx.doi.org/10.3389/fonc.2022.893124

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