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TAK-242 ameliorates epileptic symptoms in mice by inhibiting the TLR4/NF-κB signaling pathway

BACKGROUND: There is evidence that immune inflammation plays an important role in the of epilepsy. The toll-like receptor 4 (TLR4)/nuclear factor kappa beta (NF-κB) signaling pathway is a target for the treatment of epilepsy. TAK-242 is a potent TLR4 inhibitor with neuroprotective effects. No study...

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Detalles Bibliográficos
Autores principales:	Dong, Jibo, Liao, Yong, Wu, Bihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372658/ https://www.ncbi.nlm.nih.gov/pubmed/35965792 http://dx.doi.org/10.21037/atm-22-2707

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