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Air leaks in COVID-19

Coronavirus disease 2019 (COVID-19) continues to create havoc and may present with myriad complications involving many organ systems. However, the respiratory system bears the maximum brunt of the disease and continues to be most commonly affected. There is a high incidence of air leaks in patients...

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Autores principales: Juneja, Deven, Kataria, Sahil, Singh, Omender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372787/
https://www.ncbi.nlm.nih.gov/pubmed/36159609
http://dx.doi.org/10.5501/wjv.v11.i4.176
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author Juneja, Deven
Kataria, Sahil
Singh, Omender
author_facet Juneja, Deven
Kataria, Sahil
Singh, Omender
author_sort Juneja, Deven
collection PubMed
description Coronavirus disease 2019 (COVID-19) continues to create havoc and may present with myriad complications involving many organ systems. However, the respiratory system bears the maximum brunt of the disease and continues to be most commonly affected. There is a high incidence of air leaks in patients with COVID-19, leading to acute worsening of clinical condition. The air leaks may develop independently of the severity of disease or positive pressure ventilation and even in the absence of any traditional risk factors like smoking and un-derlying lung disease. The exact pathophysiology of air leaks with COVID-19 remains unclear, but multiple factors may play a role in their development. A significant proportion of air leaks may be asymptomatic; hence, a high index of suspicion should be exercised for enabling early diagnosis to prevent further deterioration as it is associated with high morbidity and mortality. These air leaks may even develop weeks to months after the disease onset, leading to acute deterioration in the post-COVID period. Conservative management with close monitoring may suffice for many patients but most of the patients with pneumothorax may require intercostal drainage with only a few requiring surgical interventions for persistent air leaks.
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spelling pubmed-93727872022-09-23 Air leaks in COVID-19 Juneja, Deven Kataria, Sahil Singh, Omender World J Virol Minireviews Coronavirus disease 2019 (COVID-19) continues to create havoc and may present with myriad complications involving many organ systems. However, the respiratory system bears the maximum brunt of the disease and continues to be most commonly affected. There is a high incidence of air leaks in patients with COVID-19, leading to acute worsening of clinical condition. The air leaks may develop independently of the severity of disease or positive pressure ventilation and even in the absence of any traditional risk factors like smoking and un-derlying lung disease. The exact pathophysiology of air leaks with COVID-19 remains unclear, but multiple factors may play a role in their development. A significant proportion of air leaks may be asymptomatic; hence, a high index of suspicion should be exercised for enabling early diagnosis to prevent further deterioration as it is associated with high morbidity and mortality. These air leaks may even develop weeks to months after the disease onset, leading to acute deterioration in the post-COVID period. Conservative management with close monitoring may suffice for many patients but most of the patients with pneumothorax may require intercostal drainage with only a few requiring surgical interventions for persistent air leaks. Baishideng Publishing Group Inc 2022-07-25 2022-07-25 /pmc/articles/PMC9372787/ /pubmed/36159609 http://dx.doi.org/10.5501/wjv.v11.i4.176 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Juneja, Deven
Kataria, Sahil
Singh, Omender
Air leaks in COVID-19
title Air leaks in COVID-19
title_full Air leaks in COVID-19
title_fullStr Air leaks in COVID-19
title_full_unstemmed Air leaks in COVID-19
title_short Air leaks in COVID-19
title_sort air leaks in covid-19
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372787/
https://www.ncbi.nlm.nih.gov/pubmed/36159609
http://dx.doi.org/10.5501/wjv.v11.i4.176
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