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A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data

BACKGROUND AND OBJECTIVES: Exome sequencing (ES) and genome sequencing (GS) are expected to be critical to further elucidate the missing genetic heritability of Alzheimer disease (AD) risk by identifying rare coding and/or noncoding variants that contribute to AD pathogenesis. In the United States,...

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Detalles Bibliográficos
Autores principales: Belloy, Michael E., Le Guen, Yann, Eger, Sarah J., Napolioni, Valerio, Greicius, Michael D., He, Zihuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372872/
https://www.ncbi.nlm.nih.gov/pubmed/35966919
http://dx.doi.org/10.1212/NXG.0000000000200012