Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child

Measles–rubella (MR) vaccine–associated encephalopathy is rare and coexistence with optic neuritis (ON) has never been reported. Only two patients (one child and one adult) had ‘MR Vaccine–associated myelin-oligodendrocyte-glycoprotein antibody (MOGAb) positive encephalopathy’. Myelin oligodendrocyt...

Descripción completa

Detalles Bibliográficos
Autores principales: Otiv, Madhumati, Botre, Abhijeet, Shah, Pawan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373146/
https://www.ncbi.nlm.nih.gov/pubmed/35966175
http://dx.doi.org/10.1177/25151355221115016
_version_ 1784767538662473728
author Otiv, Madhumati
Botre, Abhijeet
Shah, Pawan
author_facet Otiv, Madhumati
Botre, Abhijeet
Shah, Pawan
author_sort Otiv, Madhumati
collection PubMed
description Measles–rubella (MR) vaccine–associated encephalopathy is rare and coexistence with optic neuritis (ON) has never been reported. Only two patients (one child and one adult) had ‘MR Vaccine–associated myelin-oligodendrocyte-glycoprotein antibody (MOGAb) positive encephalopathy’. Myelin oligodendrocyte glycoprotein (MOG), a surface myelin protein, is the target of the immune system in this disease. We describe a critical unique case of ‘post-MR Vaccine, MOG-antibody positive Acute Disseminated Encephalo-Myelitis (ADEM) with optic neuritis’, who recovered with immunotherapy.
format Online
Article
Text
id pubmed-9373146
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-93731462022-08-13 Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child Otiv, Madhumati Botre, Abhijeet Shah, Pawan Ther Adv Vaccines Immunother Case Report Measles–rubella (MR) vaccine–associated encephalopathy is rare and coexistence with optic neuritis (ON) has never been reported. Only two patients (one child and one adult) had ‘MR Vaccine–associated myelin-oligodendrocyte-glycoprotein antibody (MOGAb) positive encephalopathy’. Myelin oligodendrocyte glycoprotein (MOG), a surface myelin protein, is the target of the immune system in this disease. We describe a critical unique case of ‘post-MR Vaccine, MOG-antibody positive Acute Disseminated Encephalo-Myelitis (ADEM) with optic neuritis’, who recovered with immunotherapy. SAGE Publications 2022-08-09 /pmc/articles/PMC9373146/ /pubmed/35966175 http://dx.doi.org/10.1177/25151355221115016 Text en © The Author(s), 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Otiv, Madhumati
Botre, Abhijeet
Shah, Pawan
Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title_full Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title_fullStr Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title_full_unstemmed Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title_short Measles–rubella vaccine–associated MOG-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
title_sort measles–rubella vaccine–associated mog-antibody positive acute demyelinating encephalomyelitis with optic neuritis in a child
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373146/
https://www.ncbi.nlm.nih.gov/pubmed/35966175
http://dx.doi.org/10.1177/25151355221115016
work_keys_str_mv AT otivmadhumati measlesrubellavaccineassociatedmogantibodypositiveacutedemyelinatingencephalomyelitiswithopticneuritisinachild
AT botreabhijeet measlesrubellavaccineassociatedmogantibodypositiveacutedemyelinatingencephalomyelitiswithopticneuritisinachild
AT shahpawan measlesrubellavaccineassociatedmogantibodypositiveacutedemyelinatingencephalomyelitiswithopticneuritisinachild

Ejemplares similares