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M2-Deficient Single-Replication Influenza Vaccine–Induced Immune Responses Associated With Protection Against Human Challenge With Highly Drifted H3N2 Influenza Strain( )

BACKGROUND: Current influenza vaccines are strain specific and demonstrate low vaccine efficacy against H3N2 influenza disease, especially when vaccine is mismatched to circulating virus. The novel influenza vaccine candidate, M2-deficient single replication (M2SR), induces a broad, multi-effector i...

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Detalles Bibliográficos
Autores principales: Eiden, Joseph, Volckaert, Bram, Rudenko, Oleg, Aitchison, Roger, Herber, Renee, Belshe, Robert, Greenberg, Harry, Coelingh, Kathleen, Marshall, David, Kawaoka, Yoshihiro, Neumann, Gabriele, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373152/
https://www.ncbi.nlm.nih.gov/pubmed/34323977
http://dx.doi.org/10.1093/infdis/jiab374