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Combining factorial and multi-arm multi-stage platform designs to evaluate multiple interventions efficiently
BACKGROUND: Factorial designs and multi-arm multi-stage (MAMS) platform designs have many advantages, but the practical advantages and disadvantages of combining the two designs have not been explored. METHODS: We propose practical methods for a combined design within the platform trial paradigm whe...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373200/ https://www.ncbi.nlm.nih.gov/pubmed/35579066 http://dx.doi.org/10.1177/17407745221093577 |