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Combining factorial and multi-arm multi-stage platform designs to evaluate multiple interventions efficiently

BACKGROUND: Factorial designs and multi-arm multi-stage (MAMS) platform designs have many advantages, but the practical advantages and disadvantages of combining the two designs have not been explored. METHODS: We propose practical methods for a combined design within the platform trial paradigm whe...

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Detalles Bibliográficos
Autores principales:	White, Ian R, Choodari-Oskooei, Babak, Sydes, Matthew R, Kahan, Brennan C, McCabe, Leanne, Turkova, Anna, Esmail, Hanif, Gibb, Diana M, Ford, Deborah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373200/ https://www.ncbi.nlm.nih.gov/pubmed/35579066 http://dx.doi.org/10.1177/17407745221093577

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